Speaker
Description
For the two three-way ANOVA models
In this talk we aim to determine the minimal sample size of the two models mentioned above given a prespecified power and we
(i) give a heuristic that the number of replicates
(ii) determine the active and inactive variance components for both ANOVA models using a surrogate fractional factorial model with variance components as factors.
(iii) determine the worst combination of active variance components for both models using a surrogate response surface model based on a Box-Behnken design. The special structure of the Box-Behnken design ensures that the used models have similar total variance.
Additionally we propose three practical methods that help reducing the number of simulations required to determine the minimal sample size.
We compare the proposed methods, present some examples and, finally, we give recommendations about which method to choose.
Classification | Mainly methodology |
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Keywords | ANOVA; approximate F-test; minimal sample size determination |