Conveners
CONTRIBUTED Clinical Statistics/Anomalies
- Jean-Michel Poggi (University of Paris-Saclay)
From the perspective of anomaly detection when data are functional and spatially dependent, we explore death counts from all causes observed along 2020 in the provinces and municipalities of Italy. Our aim is to isolate the spatio-temporal perturbation brought by COVID-19 to the Country’s expected process of mortality during the first two waves of the pandemic.
Within the framework of...
When comparing a medical treatment with placebo it is usual to apply a two-sample t-test. n1 patients are given treatment and n2 patients are given placebo. The standard assumptions for using a two-sample t-test are assumed. It is also assumed that large response values in the treatment group are desirable. Usually H0: “The distribution means are equal” is tested against H1: “The distribution...
Pocket detection is a key step inside the process of drug design and development. Its purpose is to prioritize specific areas of the protein surface with high chance of being binding sites. The primary byproduct of this is to avoid blind docking. During a blind docking, the software tries to fit the ligand into the target protein without prior knowledge, thus it scans the whole protein surface...