ENBIS Spring Meeting 2023

Session

Poster session

26 May 2023, 11:25

Building 101A, Meeting Room 1 (Copenhagen)

9. Discontinuous Galerkin solver for continuous chromatography

Jesper Frandsen (Technical University of Denmark)

26/05/2023, 11:25

Column chromatography is a workhorse unit operation for purification of proteins and pharmaceuticals. Most column chromatography unit operations are run in batch-mode although continuous chromatography has the potential to increase productivity and reduce the solvent consumption. Operating continuous chromatography requires having multiple columns in series and/or parallel. The operation is...

16. Real time predictions in the process industry using hybrid-models - a case from Viking Malt A/S

Peter Jul-Rasmussen (Technical University Of Denmark)

26/05/2023, 11:35

In the chemical-, biochemical-, and food production industries vast amounts of process data are being recorded using inline/online sensor measurements and offline laboratory measurements. Putting this process data to work through implementation of operator assistance tools, control systems, and digital twins has gained renewed interest in industry [Udugama 2020]. Introduction of Big-Data...

26. Stochastic modelling of fermentation processes: State estimation of perfusion cultivations using the Extended Kalman filter

Torine Reed Herstad (Novo Nordisk)

26/05/2023, 11:45

Mammalian cells, particularly Chinese Hamster Ovary (CHO) cells, used for the production of recombinant proteins has gained widespread popularity in recent years due to their capability to produce proteins that are more similar to those found in humans [1], an essential feature in the development of therapeutics. CHO cells are recognized as one of the most reliable mammalian cell lines due to...